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Search Results for " tumor-related protein "
Targets Recommended: Apoptosis Microtubule Associated

5

抑制剂 & 化合物

4

天然产物

2

化合物库

46

重组蛋白

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Cat. No. Product Name
L2200 酪氨酸激酶分子库

1016 compounds
1016 种酪氨酸激酶抑制剂的独特集合,可用于高通量筛选和高内涵筛选;
L1300 PI3K/Akt/mTOR 化合物库

420 compounds
420 种与PI3K/Akt/mTOR 相关的生物活性小分子化合物的特有集合,用于PI3K/Akt/mTOR 相关研究以及高通量、高内涵筛选;

化合物库

酪氨酸激酶分子库
Cat.No: L2200
Compounds: 1016
PI3K/Akt/mTOR 化合物库
Cat.No: L1300
Compounds: 420
Cat. No. Product Name Target Signaling Pathways
TQ0141 Taltobulin

HTI-286,SPA-110

Apoptosis; Microtubule Associated Apoptosis; Cytoskeletal Signaling
Taltobulin (HTI-286) 是一种三肽半胱氨酸的合成类似物,是一种微管蛋白抑制剂,在体外抑制肝肿瘤细胞增殖和体内肿瘤生长。Taltobulin 具有细胞毒性,诱导有丝分裂停滞以及凋亡 (apoptosis),可用于研究乳腺癌和与微管组织相关的疾病。
T3623 Cobimetinib

可美替尼,考比替尼,RG7420,XL518,GDC-0973

Apoptosis; MEK Apoptosis; MAPK
Cobimetinib (GDC-0973) 是一种可口服的 MEK1选择性抑制剂,抑制MEK1的IC50为4.2 nM。
T10406 Tuvusertib

M1774,ATR inhibitor 1

Apoptosis; ATM/ATR; Others; Chk Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others; PI3K/Akt/mTOR signaling
Tuvusertib (M1774) 是一种可口服的共济失调毛细血管扩张和 Rad3相关(ATR)激酶抑制剂(Ki< 1 µΜ),具有选择性和潜在的抗肿瘤活性。Tuvusertib 选择性抑制 ATR 活性,阻断丝氨酸/苏氨酸蛋白激酶检查点激酶1 (CHK1)的下游磷酸化,从而抑制 DNA 损伤检查点激活,破坏 DNA 损伤修复,诱导肿瘤细胞凋亡。
T9533 BC-LI-0186

4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide

Others Others
BC-LI-0186 (4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide) 是选择性抑制亮氨酸 tRNA 合成酶与 Ras 相关的 GTP 结合蛋白 D 相互作用(IC50=46.11 nM)。BC-LI-0186能有效抑制肿瘤相关 MTOR 突变体的特性和雷帕霉素耐药癌细胞的生长,能够用于肺癌的相关研究。
T26981 Ceralasertib formate

Ceralasertib,AZD-6738,AZD 6738,AZD6738

Ceralasertib is an orally available inhibitor of ataxia telangiectasia and rad3 related (ATR) kinase. Ceralasertib selectively inhibits ATR activity by blocking the downstream phosphorylation of the serine/threonine protein kinase CHK1. This prevents ATR-

化合物

Taltobulin
Cat.No: TQ0141
Synonym: HTI-286,SPA-110
Target: Apoptosis, Microtubule Associated
Cobimetinib
Cat.No: T3623
Synonym: 可美替尼,考比替尼,RG7420,XL518,GDC-0973
Target: Apoptosis, MEK
Tuvusertib
Cat.No: T10406
Synonym: M1774,ATR inhibitor 1
Target: Apoptosis, ATM/ATR, Others, Chk
BC-LI-0186
Cat.No: T9533
Synonym: 4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide
Target: Others
Ceralasertib formate
Cat.No: T26981
Synonym: Ceralasertib,AZD-6738,AZD 6738,AZD6738
Target:
Cat. No. Product Name Target Signaling Pathways
T3314 Perillyl alcohol

Isocarveol,Perilla alcohol,紫苏醇

Apoptosis; Endogenous Metabolite Apoptosis; Metabolism
Perillyl alcohol (Isocarveol) 是一种单萜,可在不影响正常细胞的情况下诱导肿瘤细胞凋亡。
TN1410 Asperulosidic acid

ASPA,车叶草苷酸

ERK; NF-κB MAPK; NF-κB
Asperulosidic acid (ASPA) 是从白花蛇舌草药中提取的一种环烯醚萜苷,具有抗肿瘤、抗氧化和抗炎作用。它通过抑制 NF-κB 和丝裂原活化蛋白激酶信号通路抑制炎性细胞因子释放发挥抗炎作用。
T6S1315 Oroxylin A

千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether

Virus Protease; HIF/HIF Prolyl-Hydroxylase; Autophagy Autophagy; Chromatin/Epigenetic; Metabolism; Microbiology/Virology
Oroxylin A (Baicalein 6-methyl ether) 是一种有活性的黄酮,具有较强的抗癌作用。
T81484 Phorbol 12-tiglate

Phorbol12-tiglate为Phorbol衍生物,后者乃巴豆油水解产物,可激活蛋白激酶C,进而促进肿瘤发展。Phorbol及其衍生物在生物医学领域,广泛用于建立致癌模型研究。

天然产物

Perillyl alcohol
Cat.No: T3314
Synonym: Isocarveol,Perilla alcohol,紫苏醇
Target: Apoptosis, Endogenous Metabolite
Asperulosidic acid
Cat.No: TN1410
Synonym: ASPA,车叶草苷酸
Target: ERK, NF-κB
Oroxylin A
Cat.No: T6S1315
Synonym: 千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether
Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy
Phorbol 12-tiglate
Cat.No: T81484
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-00564 PLXDC2 Protein, Mouse, Recombinant (His)

Tumor endothelial marker 7-related pro...

Mouse HEK293 Cells
Mouse Plexin domain-containing protein 2(PLXDC2) is a single-pass type I membrane protein. The protein is expressed in tumor endothelium and in vessels of some normal tissues, such as the muscle and lung. PLXDC2 can interact with CTTN, and may play a role in tumor angiogenesis.
TMPH-02599 C1QTNF6 Protein, Mouse, Recombinant (His & SUMO)

Complement C1q tumor necrosis factor-related

Mouse E. coli
C1QTNF6 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-02600 C1QL3 Protein, Mouse, Recombinant (His & Myc)

C1ql,Gliacolin,C1q and tumor necrosis factor-re...

Mouse Baculovirus Insect Cells
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC1 and PCK1 and hence decreases de novo glucose production.
TMPH-02555 C1QL1 Protein, Mouse, Recombinant (His)

C1q and tumor necrosis factor-related ...

Mouse P. pastoris (Yeast)
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses.
TMPJ-01304 C1QTNF1 Protein, Human, Recombinant (His)

C1QTNF1,G Protein-Coupled Receptor-Interacting ...

Human HEK293 Cells
C1QTNF1 is a secreted protein,contains 1 C1q domain and 1 collagen-like domain. C1qTNF proteins constitute a highly conserved family of Acrp30/Adiponectin paralogs that share a modular organization comprising an N-terminal signal peptide, a short variable region, a collagenous domain and a C-terminal globular domain. C1qTNF proteins are predicted to have trimeric structures that assemble into hexameric and higher order molecular forms. C1QTNF1 is a novel adipokine, providing a significant framew...
TMPJ-00981 PTX3 Protein, Mouse, Recombinant (His)

alpha-induced protein 5,pentraxin 3, long,pentaxin-...

Mouse HEK293 Cells
Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It’s subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator...
TMPH-01129 C1QTNF3 Protein, Human, Recombinant (His)

C1QTNF3,CORS26,Collagenous repeat-containing sequence 26 kDa...

Human E. coli
C1QTNF3 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-00110 GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His)

Tnfrsf18,GITR-D,CD357,AITR,Tumor necrosis factor re...

Mouse HEK293 Cells
Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1, TRAF2, and...
TMPH-01130 C1QTNF3 Protein, Human, Recombinant (His & Myc)

Secretory protein CORS26,Collagenous repeat-contain...

Human Baculovirus Insect Cells
C1QTNF3 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPH-02598 C1QTNF3 Protein, Mouse, Recombinant (His)

Secretory protein CORS26,C1QTNF3,Complement C1q

Mouse HEK293 Cells
C1QTNF3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 26.6 kDa and the accession number is Q9ES30.
TMPJ-01372 Cornulin Protein, Human, Recombinant (His)

Tumor-Related Protein,58 kDa Heat...

Human E. coli
Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. Cornulin involves in the mucosal/epithelial immune response and epidermal differentiation. Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and ...
TMPH-02497 Adipolin Protein, Mouse, Recombinant (His)

Adipose-derived insulin-sensitizing factor,Complement C1q

Mouse Baculovirus Insect Cells
Adipolin Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 33.9 kDa and the accession number is Q8R2Z0.
TMPH-02496 Adipolin Protein, Mouse, Recombinant (E. coli, His)

C1qtnf12,Ctrp12,Complement C1q tumor necrosis facto...

Mouse E. coli
Adipolin Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 37.0 kDa and the accession number is Q8R2Z0.
TMPJ-00546 EFNA1 Protein, Human, Recombinant (hFc)

TNFAIP4,LERK1,Tumor Necrosis Factor α-Induced P...

Human HEK293 Cells
Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the...
TMPJ-00274 LTBR Protein, Human, Recombinant (His)

TNFCR,Tumor Necrosis Factor Receptor Superfamily Me...

Human HEK293 Cells
Tumor necrosis factor receptor superfamily member 3, also known as Lymphotoxin-beta receptor,Tumor necrosis factor C receptor,Tumor necrosis factor receptor 2-related protein,Tumor necrosis factor receptor type III,LTBR,TNFCR, TNFR3 and TNFRSF3, is a member of the tumor necrosis factor (TNF) family of receptors. LTBR is a single-pass type I membrane protein and contains four TNFR-Cys repeats. It is expressed on the surface of most cell types, but not on T and B lymphocytes. LTBR and its ligand p...
TMPJ-00152 CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated

CD40 Ligand,TNF-Related Activation Protein...

Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-6xHis-Avi tag. The predicted molecular weight is 23-28 KDa and the accession number is P29965.
TMPJ-00150 CD40 Ligand Protein, Human, Recombinant (Mammalian)

CD40LG,Tumor Necrosis Factor Ligand Superfamily Mem...

Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (Mammalian) is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-18 KDa and the accession number is P29965.
TMPJ-00151 CD40 Ligand Protein, Human, Recombinant

CD40LG,CD40 Ligand,TRAP,TNF-Related Activation ...

Human E. coli
CD40 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 KDa and the accession number is P29965.
TMPJ-00153 CD40 Ligand Protein, Human, Recombinant (His & Flag)

CD40LG,Tumor Necrosis Factor Ligand Superfamily Mem...

Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 19-24 KDa and the accession number is P29965.
TMPY-02869 MMP-12 Protein, Human, Recombinant (catalytic domain)

HME,ME,MMP-12,MME,matrix metallopeptidase 12

Human E. coli
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ...
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST)

v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...

Human Baculovirus Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPH-01048 CEACAM5 Protein, Human, Recombinant (E398K, His)

Carcinoembryonic antigen-related cell adhesion mole...

Human HEK293 Cells
Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells.; (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5...
TMPK-00134 ULBP-1 Protein, Human, Recombinant (His & Avi)

ALCAN-beta,ALCAN-β,ULBP-1,MULT-1,NKG2D ligand 1,AET1I,NKG2DL...

Human HEK293 Cells
Cell surface proteins major histocompatibility complex (MHC) class I-related chain A (MICA) and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor transformation and can activate human natural killer (NK) cells. ULBP-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.2 kDa and the accession number is Q9BZM6.
TMPK-00135 ULBP-1 Protein, Human, Recombinant (His & Avi), Biotinylated

ALCAN-β,NKG2D ligand 1,ULBP-1,NKG2DL,MULT-1,ULBP1,ALCAN-beta...

Human HEK293 Cells
Cell surface proteins major histocompatibility complex (MHC) class I-related chain A (MICA) and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor transformation and can activate human natural killer (NK) cells. ULBP-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.2 kDa and the accession number is Q9BZM6.
TMPK-00249 TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated

TNFRSF10D,CD264,TRUNDD,DCR2,RSF10D,TRAILR4

Human HEK293 Cells
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL-R2/DR5 as well as TRAIL-R3/DcR1 and TRAIL-R4/DcR2 were significantly higher expressed in advanced tumour stages. TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is ...
TMPK-00248 TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi)

DCR2,TNFRSF10D,RSF10D,CD264,TRUNDD,TRAILR4

Human HEK293 Cells
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL-R2/DR5 as well as TRAIL-R3/DcR1 and TRAIL-R4/DcR2 were significantly higher expressed in advanced tumour stages. TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 19.4 kDa and t...
TMPJ-00999 UBE2D1 Protein, Human, Recombinant (GST)

Ubiquitin-conjugating enzyme E2(17)KB 1,UB,UbcH5,UBC5A,Stimu...

Human E. coli
Ubiquitin-conjugating enzyme E2 D1(UBE2D1)belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transc...
TMPJ-01412 LRP-12 Protein, Human, Recombinant (His)

LRP-12,ST7,Suppressor of Tumorigenicity 7 Prote...

Human HEK293 Cells
Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 contains 2 CUB domain and 5 LDL-receptor class A domain. LRP12 has been shown to interact with GNB2L1, ZFYVE9 and ITGB1BP3. LRP12 is a receptor probably, which may be involved in the internalization of lipophilic molecules and/or signal transduction. In addition, LRP12 may act as ...
TMPY-01416 OLFM4 Protein, Human, Recombinant (His)

hGC-1,GC1,OLM4,bA209J19.1,GW112,olfactomedin 4,OlfD,hOLfD,UN...

Human HEK293 Cells
Olfactomedin-4, also known as G-CSF-stimulated clone 1 protein, Antiapoptotic protein GW112, and OLFM4, is a secreted protein that contains one olfactomedin-like domain. The OLFM4 gene was recently reported to inhibit various apoptotic pathways and promote the proliferation of cancer cells, suggesting that OLFM4 might serve as a diagnostic marker for human cancers. Thus, OLFM4 mRNA might be a useful tool to support the diagnosis of cancer, irrespective of the clinical stages. It is overexpressed...
TMPY-02572 TXNDC17 Protein, Human, Recombinant

thioredoxin domain containing 17,TXNL5,TRP14

Human E. coli
Thioredoxin-related protein of 14 kDa (TRP14, also called TXNDC17 for thioredoxin domain containing 17, or TXNL5 for thioredoxin-like 5) is an evolutionarily well-conserved member of the thioredoxin (Trx)-fold protein family that lacks activity with classical Trx1 substrates. TXNDC17 is a novel 14-kDa disulfide reductase of the TXN (thioredoxin) family. TXNDC17 is involved in the TNF (tumor necrosis factor) signaling pathway. Moreover, TXNDC17 plays an important role in Taxol resistance via enha...
TMPJ-00680 ANGPTL7 Protein, Human, Recombinant (His)

CDT6,Cornea-derived transcript 6 protein,Angiopoiet...

Human HEK293 Cells
Angiopoietin-like 7 (ANGPTL7) is a secreted glycoprotein that is structurally related to the angiopoietins. Members of this protein family contain an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL7 shares 89% aa sequence identity with mouse and rat ANGPTL7. It is secreted as a 45-50kDa monomer that forms disulfide-linked homotrimers and tetramers via the coiled coil domain. ANGPTL7 is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated ...
TMPJ-00578 CEACAM21 Protein, Human, Recombinant (His)

Carcinoembryonic antigen-related cell adhesion mole...

Human HEK293 Cells
Carcinoembryonic antigen-related cell adhesion molecule 21 is a protein that in humans is encoded by the CEACAM21 gene. It belongs to the immunoglobulin superfamily. CEA family.containing 1 Ig-like C2-type (immunoglobulin-like) domain.It was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been a...
TMPY-02651 p63 Protein, Human, Recombinant (His & GST)

p40,TP53L,RHS,B(p51A),p51,KET,NBP,B(p51B),OFC8,tumor

Human Baculovirus Insect Cells
Tumor protein p63 is a protein also known as transformation-related protein 63, TP63, and p63. Tumor protein p63 / p63 is a member of the p53 family of transcription factors whose members P53, p63, and p73 have similar features in their gene structures and functions. An animal model, p63-/- mice has been useful in difining the role p63 plays in the development and maintenance of stratified epithelial tissues. This p63 encoding protein p63 has a dramatic impact on replenishment of cutaneous epith...
TMPY-01816 Pentraxin 3 Protein, Human, Recombinant (His)

TNFAIP5,pentraxin 3,PTX3,TSG-14

Human HEK293 Cells
Pentraxin-related protein PTX3, also known as Tumor necrosis factor alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14, PTX3 and TNFAIP5, is a secreted protein that contains one pentaxin domain. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. Pentraxins are a family of evolutionarily conserved multifunctional pattern-recognition proteins characterized by a cycl...
TMPY-04547 PBK/TOPK Protein, Human, Recombinant (His)

HEL164,Nori-3,CT84,TOPK,PDZ binding kinase,SPK

Human Baculovirus Insect Cells
PDZ binding kinase (PBK), also known as TOPK (T-LAK cell-originated protein kinase), is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family, and has all the characteristic protein kinase subdomains and a C-terminal PDZ-binding T/SXV motif. PBK is expressed in the testis restrictedly expressed in outer cell layer of seminiferous tubules, as well as placenta. PBK may be enrolled in the activation of lymphoid cells and support testicular fun...
TMPY-04936 BCL2A1 Protein, Human, Recombinant (His)

BFL1,ACC1,ACC-2,GRS,ACC-1,HBPA1,BCL2 related pr...

Human E. coli
B-cell lymphoma 2-related protein A1 (BCL2A1) is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs. Immunohistochemical expression of Wnt11 and BCL2A1 in complete moles and normal villi. Bcl2 family proteins control mitochondrial apoptosis and its members exert critical cell type and differentiation stage-specific functions, acting as barriers against autoimmunity or transformation. Anti-apoptotic Bcl2a1/Bfl1/A1 is frequently der...
TMPY-02759 Kallikrein 6/KLK6 Protein, Human, Recombinant (His)

kallikrein-related peptidase 6,PRSS18,PRSS9,Klk7,Bs...

Human HEK293 Cells
KLK6 (kallikrein-related peptidase 6), also known as Klk7, belongs to the peptidase S1 family, Kallikrein subfamily. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK6 is a serine protease that exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Klk7 sh...
TMPY-02440 SAP/SH2D1A Protein, Human, Recombinant (His)

XLPD,EBVS,DSHP,SAP,MTCP1,IMD5,SH2 domain containing 1A,LYP,S...

Human E. coli
SH2domain-containing protein 1A (SH2D1A / SAP) is a 128 amino acid protein, containing a single Src homology 2 (SH2) domain, flanked by 5 amino acids at the N-terminus and 25 amino acids at the C-terminus. The absence of a catalytic domain and the presence of an SH2domain suggest that SH2D1A regulates one or more signal transduction pathways. SH2D1A interacts with signaling lymphocytic activation molecule (SLAM), which is a transmembrane protein expressed on the surface of activated T and B cell...
TMPY-02084 Thioredoxin 2/TRX2 Protein, Human, Recombinant (His)

MT-TRX,RP5-1119A7. 13-005,TRX2,MTRX,thioredoxin 2

Human E. coli
Thioredoxin-2, also known as TXN2, MTRX and TRX2, is a member of the thioredoxin family. Tryparedoxins (TXN) are thioredoxin-related proteins which, as trypanothione:peroxiredoxin oxidoreductases, constitute the trypanothione-dependent antioxidant defense and may also serve as substrates for ribonucleotide reductase in trypanosomatids. Thioredoxin-2 / TXN2 contains one thioredoxin domain. It is widely expressed in adult (at protein level) and fetal tissues. Human Thioredoxin-2 / TXN2 is a small ...
TMPY-02712 Serpin B3 Protein, Human, Recombinant (His)

T4-A,HsT1196,serpin peptidase inhibitor, clade B (ovalbumin)...

Human Baculovirus Insect Cells
SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. SERPINB3 is expressed in some hepatocellular carcinoma (at protein level). Its expression is closely related to cellular differentiation in both normal and malignant squamous cells. It seems to also be...
TMPY-01771 Latexin Protein, Mouse, Recombinant (His)

latexin

Mouse E. coli
Latexin, also known as endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor, TCI, ECI, and LXN, is a cytoplasm protein that belongs to the protease inhibitor I47 (latexin) family. It is highly expressed in the heart, prostate, ovary, kidney, pancreas, and colon. Latexin / LXN is the only known endogenous specific inhibitor of zinc-dependent metallocarboxypeptidases (MCPs) present in mammalians so far. Latexin is originally identified as a molecular marker for the regional spe...
TMPY-01204 SMYD2 Protein, Human, Recombinant (His)

ZMYND14,SET and MYND domain containing 2,HSKM-B,KMT3C

Human Baculovirus Insect Cells
SET and MYND domain-containing protein 2, also known as HSKM-B, SMYD2, and KMT3C, is a member of the SMYD protein family. It contains one MYND-type zinc finger and one SET domain. Not much is known about SMYD2. However, the interest in better understanding the roles of SMYD2 has grown because of reports indicating that SMYD2 methylates p53 and histone H3. In Xenopus, SMYD1 and SMYD2 were expressed in various muscle tissues and related to muscle cell differentiation. SMYD2 mRNA is most highly exp...
TMPY-02516 Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc)

interferon, α10,interferon, alpha 10,IFN-alphaC,MGC119879,干扰...

Human HEK293 Cells
Interferon alpha-10 (IFNA10) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogen...
TMPY-04260 p38 Protein, Human, Recombinant (His)

mitogen-activated protein kinase 14,CSPB1,PRKM14,RK...

Human Baculovirus Insect Cells
MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. MAPK14 can be detected in the brain, heart, placenta, pancreas, and skeletal muscle and it is expressed to a lesser extent in the lung, liver, and kidney. MAPK14 is activated by various environmental stresses ...
TMPY-00918 SFRP1 Protein, Human, Recombinant (His)

SARP2,secreted frizzled-related protein 1,...

Human HEK293 Cells
Secreted frizzled-related protein 1, also known as sFRP1, is a 35 kDa prototypical member of the SFRP family. SFRP family consists of five secreted glycoproteins in humans acting as extracellular signaling ligands. Each is approximately 3 amino acids in length and contains a cysteine-rich domain (CRD) that shares 3-5% sequence homology with the CRD of Frizzled (Fz) receptors, a putative signal sequence, and a conserved hydrophilic carboxy-terminal domain. SFRPs act as soluble modulators of Wnt s...
TMPY-00564 MCP-4 Protein, Human, Recombinant (His)

MCP-4,CCL13,SCYL1,NCC-1,MCP4,NCC1,CKb10,SCYA13,chemokine (C-...

Human P. pastoris (Yeast)
Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eosinphils to inflammatory sites. CCL13/MCP-4, is a CC family chemokine that is chemoattractant for eosinophils, basophils, monocytes, macrophages, immature dendritic cells, and T cells, and its capable of inducing crucial immuno-modulatory responses through its effects on epithelial, muscular and endothelial cells. Similar to other CC chem...

重组蛋白

PLXDC2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00564
Species: Mouse
Expression System: HEK293 Cells
C1QTNF6 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02599
Species: Mouse
Expression System: E. coli
C1QL3 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02600
Species: Mouse
Expression System: Baculovirus Insect Cells
C1QL1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02555
Species: Mouse
Expression System: P. pastoris (Yeast)
C1QTNF1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01304
Species: Human
Expression System: HEK293 Cells
PTX3 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00981
Species: Mouse
Expression System: HEK293 Cells
C1QTNF3 Protein, Human, Recombinant (His)
Cat.No: TMPH-01129
Species: Human
Expression System: E. coli
GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His)
Cat.No: TMPJ-00110
Species: Mouse
Expression System: HEK293 Cells
C1QTNF3 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01130
Species: Human
Expression System: Baculovirus Insect Cells
C1QTNF3 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02598
Species: Mouse
Expression System: HEK293 Cells
Cornulin Protein, Human, Recombinant (His)
Cat.No: TMPJ-01372
Species: Human
Expression System: E. coli
Adipolin Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02497
Species: Mouse
Expression System: Baculovirus Insect Cells
Adipolin Protein, Mouse, Recombinant (E. coli, His)
Cat.No: TMPH-02496
Species: Mouse
Expression System: E. coli
EFNA1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00546
Species: Human
Expression System: HEK293 Cells
LTBR Protein, Human, Recombinant (His)
Cat.No: TMPJ-00274
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00152
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (Mammalian)
Cat.No: TMPJ-00150
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein, Human, Recombinant
Cat.No: TMPJ-00151
Species: Human
Expression System: E. coli
CD40 Ligand Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-00153
Species: Human
Expression System: HEK293 Cells
MMP-12 Protein, Human, Recombinant (catalytic domain)
Cat.No: TMPY-02869
Species: Human
Expression System: E. coli
C-ABL/ABL1 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04396
Species: Human
Expression System: Baculovirus Insect Cells
CEACAM5 Protein, Human, Recombinant (E398K, His)
Cat.No: TMPH-01048
Species: Human
Expression System: HEK293 Cells
ULBP-1 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00134
Species: Human
Expression System: HEK293 Cells
ULBP-1 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00135
Species: Human
Expression System: HEK293 Cells
TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00249
Species: Human
Expression System: HEK293 Cells
TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00248
Species: Human
Expression System: HEK293 Cells
UBE2D1 Protein, Human, Recombinant (GST)
Cat.No: TMPJ-00999
Species: Human
Expression System: E. coli
LRP-12 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01412
Species: Human
Expression System: HEK293 Cells
OLFM4 Protein, Human, Recombinant (His)
Cat.No: TMPY-01416
Species: Human
Expression System: HEK293 Cells
TXNDC17 Protein, Human, Recombinant
Cat.No: TMPY-02572
Species: Human
Expression System: E. coli
ANGPTL7 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00680
Species: Human
Expression System: HEK293 Cells
CEACAM21 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00578
Species: Human
Expression System: HEK293 Cells
p63 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-02651
Species: Human
Expression System: Baculovirus Insect Cells
Pentraxin 3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01816
Species: Human
Expression System: HEK293 Cells
PBK/TOPK Protein, Human, Recombinant (His)
Cat.No: TMPY-04547
Species: Human
Expression System: Baculovirus Insect Cells
BCL2A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04936
Species: Human
Expression System: E. coli
Kallikrein 6/KLK6 Protein, Human, Recombinant (His)
Cat.No: TMPY-02759
Species: Human
Expression System: HEK293 Cells
SAP/SH2D1A Protein, Human, Recombinant (His)
Cat.No: TMPY-02440
Species: Human
Expression System: E. coli
Thioredoxin 2/TRX2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02084
Species: Human
Expression System: E. coli
Serpin B3 Protein, Human, Recombinant (His)
Cat.No: TMPY-02712
Species: Human
Expression System: Baculovirus Insect Cells
Latexin Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01771
Species: Mouse
Expression System: E. coli
SMYD2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01204
Species: Human
Expression System: Baculovirus Insect Cells
Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02516
Species: Human
Expression System: HEK293 Cells
p38 Protein, Human, Recombinant (His)
Cat.No: TMPY-04260
Species: Human
Expression System: Baculovirus Insect Cells
SFRP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00918
Species: Human
Expression System: HEK293 Cells
MCP-4 Protein, Human, Recombinant (His)
Cat.No: TMPY-00564
Species: Human
Expression System: P. pastoris (Yeast)
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